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Krembil Research, Toronto, sees pure Maple syrup benefit in Alzheimer’s
Wednesday, 16 March, 2016, 08 : 00 AM [IST]
Our Bureau, Bengaluru
Krembil Research Institute of the University of Toronto has highlighted the importance of pure Maple syrup extract, which is seen to benefit prevention of Alzheimer’s disease.

According to the findings of a study presented by Dr Donald Weaver, director, Krembil Research Institute of the University of Toronto, an extract of maple syrup may help prevent the misfolding and clumping of two types of proteins found in brain cells – beta amyloid and tau peptide. When cellular proteins fold improperly and clump together, they accumulate and form the plaque that is involved in the onset of Alzheimer's and other brain diseases.

At the two-day symposium organised by the American Chemical Society (ACS), a group of international scientists shared promising results of 24 studies exploring the beneficial effects of natural products on the prevention of neurodegenerative diseases, particularly Alzheimer’s disease. For the first time at this symposium, real Maple syrup was included among the healthful functional foods that show promise in protecting brain cells against the kind of damage found in Alzheimer’s disease.

In yet another research findings presented at the symposium, it was highlighted that a pure Maple syrup extract also prevented the fibrillation (tangling) of beta amyloid proteins and had neuro-protective effects in rodent’s primary immune brain cells, a decrease of which is associated with Alzheimer’s disease and other neurological problems.

The Maple syrup extract also prolonged the lifespan of an Alzheimer’s roundworm model in vivo. This study was conducted out of the University of Rhode Island, in collaboration with researchers at Texas State University and was led by Dr Navindra P Seeram, associate professor, department of biomedical and pharmaceutical sciences, College of Pharmacy, University of Rhode Island, USA.

“Natural food products such as green tea, red wine, berries, curcumin and pomegranates continue to be studied for their potential benefits in combatting Alzheimer’s disease. And now, in preliminary laboratory-based Alzheimer’s disease studies, phenolic-enriched extracts of Maple syrup from Canada showed neuroprotective effects, similar to resveratrol, a compound found in red wine. However, further animal and eventually human studies would be required to confirm these initial findings.” said Dr Seeram.

The Federation of Quebec Maple Syrup Producers is committed to investing in scientific research to help better understand the link between food and health. There are over 100 bioactive compounds, some of which have anti-inflammatory properties.
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