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Saccharin: Safety threshold increased
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Friday, 22 November, 2024, 08 : 00 AM [IST]
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Parma - Italy
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EFSA has concluded that saccharin is safe for human consumption and increased the acceptable daily intake (ADI) from 5 to 9 mg/kg of body weight per day, in a scientific opinion published.
The ADI, which reflects the safe amount of a substance that can be consumed daily over a lifetime, covers saccharin and its sodium, calcium and potassium salts (E 954). The previous ADI was set in 1995 based on the increased incidence of bladder tumours observed in rat studies. However, there is now scientific agreement that these tumours are specific to male rats and not relevant to humans.
EFSA experts have reviewed all available data and concluded that saccharin does not cause DNA damage and that it is unlikely that its consumption is associated with cancer risk in humans.
In addition, consumer exposure is below the newly derived ADI, meaning that there is no health risk.
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